Raw Liver |
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Increases available Heart Containers by 2 and completely restores health. |
The Relic |
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Isaac is followed by a small blue cross that will drop a Soul Heart every 5 rooms. |
Robo-Baby |
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Follows Isaac around, shooting enemies with an eye laser similar to Technology. |
Robo-Baby 2.0 |
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Fires lasers at any enemy in its line of sight and moves based onthe direction Isaac is firing tears |
Roid Rage |
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Increases speed and range. |
Rosary |
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Adds 3 Soul Hearts and increases the chance for The Bible to appear in the Shop. |
Rotten Baby |
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A familiar that spawns Blue Flies. |
Rotten Meat |
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Adds one heart container. |
Rubber Cement |
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Tears bounce off walls and obstacles (including enemies). |
Sack Of Pennies |
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Isaac is followed by a small bag that drops a coin every 2 rooms. Usually a penny, sometimes a nickel. |
Sacred Heart |
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Increases damage and range while reducing shot speed and grants homing tears. Replenishes all Red Hearts and gives one Soul Heart upon pickup. |
Sacrificial Dagger |
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Dagger orbits Isaac, dealing very high damage. |
Sad Bombs |
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+5 Bombs. Upon exploding, bombs shoot 8 tears off in every direction, similar to Tammy's Head. The tears are affected by any tear modifiers Isaac has on his own tears. |
The Sad Onion |
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Increases Tears by 0.7. |
Safety Pin |
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Increases range and shot speed, while adding 1 Black Heart. |
Sagittarius |
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Increases speed by +0.2 and grants piercing tears. |
Samson's Chains |
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Pull a chain and ball behind you that will damage enemies on contact and is able to break stones. |
Scapular |
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Once per room, when Isaac is reduced to his last half red Heart, the aura around his head temporarily vanishes and he is granted one Soul Heart. |
Scorpio |
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Grants poison tears, which deal damage over time when inflicted. |
Screw |
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Tears and shot speed up. |
Sharp Plug |
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Using an activated item while it's not charged will charge it and Sharp Plug does 2 full heart damage to Isaac |
Sissy Longlegs |
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Wanders about the room, occasionally spawning blue Spiders. |
Sister Maggy |
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A Familiar that follows Isaac around shooting blood tears. |
Skatole |
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All types of fly except Boom Fly and Red Boom Fly become passive and slowly move towards Isaac. Does not prevent contact damage. |
Skeleton Key |
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Sets your key count to the maximum of 99. |
The Small Rock |
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Increases damage by 1. |
Smart Fly |
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After Isaac takes damage, this fly will deal continuous touch damage to whatever enemy caused the damage until it is dead. The fly will then systematically attack 1 enemy at a time until the room is cleared. |
SMB Super Fan! |
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Increases all stats. |
A Snack |
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Adds 1 Heart Container. |
Soy Milk |
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Tears shrink and do much less damage, but fire in very rapid succession. |
The Soul |
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Grants two Soul Hearts. Isaac now repels enemy projectiles. |
Speed Ball |
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Speed and Shot Speed increase. |
Spelunker Hat |
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Reveals type of adjacent rooms, including location for secret rooms and super secret rooms. |
Spider Bite |
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Adds a chance to shoot slowing tears, reducing speed of enemy movement and any projectile fired by them. |
Spider Baby |
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When hit, spawn up to 2 Blue Spider. |
Spirit Of The Night |
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Grants spectral tears and flight. |
Spoon Bender |
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Grants Isaac homing tears. |
Squeezy |
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Increases tears by 0.4, and spawns 2 Soul Hearts pickups. |
Starter Deck |
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Isaac can hold 2 cards at once and all pills are replaced by cards. |
Steam Sale |
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Reduces all Shop prices by 50%, rounded down when an item, rounded up when a pickup. |
Stem Cells |
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Adds one filled Heart Container and increases Shot Speed. |
Steven |
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Increases Damage by 1. |
Stigmata |
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Increases damages, and adds 1 heart container. |
Stop Watch |
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Automatically inflicts slow to all enemies in every room. |
Strange Attractor |
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Pick Ups, Chests and Monsters are magnetically attracted to your tears. |
Super Bandage |
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Grants one Heart Container and gives 2 Soul Hearts. |
Synthoil |
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Increases damage and range. |
Taurus |
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Speed down, gains speed while in a room with enemies until gaining My Little Unicorn effect for a few seconds. |
Tech.5 |
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Grants a unlimited range piercing laser with random rate of fire that does not replace tears. The laser might occasionally fire with the effect of a random item or trinket, such as Hook Worm, Spoon Bender or Tiny Planet. |
Technology |
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Replaces tears with a piercing laser with unlimited range. |
Technology 2 |
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Decreases damage and replaces right eye tears with a unlimited range, piercing laser which fires continuously. |
Tiny Planet |
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Range up and makes shot tears revolve around Isaac until they drop. |
The Negative |
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If the character has half a red heart or no red hearts after taking damage, it triggers The Necronomicon effect, damaging all enemies in the room. Also allows entrance into the Dark Room. |
The Polaroid |
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If the character has half a red heart or no red hearts after taking damage, it triggers the Book Of Shadows effect, creating a shield that nullifies all types of damage for 7 seconds. Also allows entrance into The Chest. |
There's Options |
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There will be 2 items available to chose from after defeating a boss. Choosing 1 item causes the other to disappear. Shop item. |
Thunder Thighs |
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Destroys rocks upon contact with Isaac. Adds one heart, and Lowers Speed. |
Toothpicks |
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Increases tears and shot speed. |
Torn Photo |
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Tears + Shot speed up. |
Tough Love |
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Adds a chance to shoot a tooth instead of a tear, which deals greater damage than regular tears. |
Transcendence |
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Grants flight. |
Treasure Map |
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Reveals all rooms for every floor. However, it does not reveal icons or secret rooms. |
Trinity Shield |
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Isaac gains a shield that will protect him from enemy shots. |
The Wafer |
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All sources of damage that would cause one heart loss are reduced to half heart instead. |
Whore Of Babylon |
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Increases damage and speed whenever the character health is half red heart or less (one red heart for Eve). |
Wire Coat Hanger |
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Increases Tears by 0.7. |
Wooden Spoon |
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Increases speed by 0.3. |
Virgo |
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Grants a chance to trigger the Book Of Shadows effect upon taking damage, creating a shield that nullifies all types of damage for 7 seconds. Also converts "bad pills" into "good pills". |
The Virus |
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Inflicts poison to enemies who make contact with Isaac. |
X-Ray Vision |
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Reveals and opens all Secret Room and Super Secret Room entrances. |